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. 2018 Aug 9;13(8):e0202031. doi: 10.1371/journal.pone.0202031

Table 3. Clinical presentations of severe malaria among patients admitted in three hospitals in Western Kenya from August 2015 to October 2016.

Clinical  Variable Hospital name P-value
category Marani Mukumu Kombewa
(n = 578) (n = 254) (n = 412)  
Age group <5 169 (29.2%) 44 (17.3%) 259 (62.8%)  
5–14 206 (35.6%) 79 (31.1%) 65 (15.8%)  
≥15 203 (35.1%) 131 (51.5%) 88 (21.4%) <0.001
Sex Female 304 (52.6%) 130 (51.2%) 215 (52.2%)  
Male 274 (47.4%) 124 (48.8%) 197 (47.8) >0.05
Treatment before Yes 254 (43.9%) 74 (29.1%) 23 (5.6%) <0.001 
admission
Comorbidity Yes 53 (9.2%) 09 (3.6%) 46 (11.2%)  <0.05
Admission  Mean 2.1 ± 2.25 2.7 ± 1.36 4.59 ± 1.90 <0.001
length (days)
Clinical Hyperpyrexia 127 (21.9%) 120 (47.2%) 118 (28.6%) <0.001
features Respiratory        
Distress 26 (4.5%) 41 (16.1%) 26 (6.3%) <0.001
Hypoglycaemia 1 (0.1%) 2 (0.78%) 2 (0.49%) *
Severe anaemia 18 (3.1%) 9 (3.5%) 58 (14.3%) <0.001
Signs of shock 30 (5.2%) 27 (10.6%) 60 (14.1) <0.001
Coma 2 (0.3%) 5 (1.9%) 4 (0.9%) *
Prostration 226 (39.1%) 140 (55.1%) 249 (60.6%) <0.001
Convulsions 52 (8.9%) 9 (3.5%) 89 (21.6%) <0.001
Persistent        
Vomiting 100 (17.3%) 65 (25.6%) 251 (60.7%) <0.001
Jaundice 13 (2.2%) 6 (2.3%) 3 (0.7%) >0.05
Hyperparastemia 234 (40.4%) 101 (39.8%) 127 (30.8%) <0.05

*Not compared because of small number of observations