Fig 6. Inversions accelerate the formation of hybrid incompatibilities.

(A) Polymorphic inversions arise in the ancestor of the two species. (B) Restricted recombination between the inversions leads to accumulating divergence (red, blue) distinct from collinear regions of the genome (grey). (C) Incomplete sorting of the inversions between two isolated populations generates immediate divergence between the two populations. (D) Preexisting divergence increases the chance of hybrid incompatibilities forming in the inverted regions as compared to the collinear regions.