. 2018 Jul 30;14(7):e1007563. doi: 10.1371/journal.pgen.1007563

Table 2. Proteins with enriched binding to the STL1 and GPD1 mRNAs identified by MS.

			Enrichment peptides				Enrichment TopAny
Category	Gene	Function	GPD1/ASH1	STL1/ASH1	GPD1/HYP2	STL1/HYP2	GPD1/ASH1	STL1/ASH1	GPD1/HYP2	STL1/HYP2
mRNA binding	LSM1	Decay	1,50^*^§	2,11^*^§	1,38^*	1,99^*^§	2,80	3,59	1,33	2,11
	LSM2	Splicing and decay	1,86^*^§	1,70^*^§	1,15^*	0,99^*	2,17	2,48	1,66	1,97
	LSM4	Splicing and decay	1,39^*	1,47^*	1,93^*^§	2,00^*^§	2,69^*^§	3,17^*^§	2,47^*^§	2,95^*^§
	LSM5	Splicing and decay	0,71	0,57	0,98	0,84	3,48^*^§	4,25^*^§	2,18^*^§	2,94^*^§
	LSM6	Splicing and decay	-	-	2,15	2,77	13,45^*^§	14,07^*^§	2,02^*^§	2,64^*^§
	PAT1	Decay	1,99^*^§	2,08^*^§	1,84^*^§	1,92^*^§	2,37^*^§	2,83^*^§	2,38^*^§	2,83^*^§
	EDC3	Decay	2,27	2,50^*^§	1,93	2,17	4,46^*^§	4,52^*^§	1,77^*^§	1,83^*^§
	PAP1	mRNA polyadenylation and transport	1,05	0,93	0,75	0,62	2,69^*^§	1,76^*^§	1,31^*	0,38^*
rRNA binding	EMG1	Ribosomal small subunit biogenesis	0,92	0,89	0,42	0,39	3,47^*^§	3,83^*^§	-0,64^*	-0,28^*
Other functions	PHO8	Nicotinamide nucleotide metabolic process	1,69^*^§	1,55^*^§	8,07^*^§	7,93^*^§	9,70^*^§	11,74^*^§	7,69^*^§	9,73^*^§
	GLO2	Methylglyoxal catabolic process	12,03^*^§	11,49^*^§	4,62^*^§	4,08^*^§	17,13^*^§	15,39^*^§	5,99^*^§	4,24^*^§
	HBT1	Cell morphogenesis	0,33	0,12	0,08	-0,13	2,54^*^§	4,58^*^§	2,62^*^§	4,66^*^§
	SAC7	Controls organization of the actin cytoskeleton	7,75^*^§	8,17^*^§	7,43^*^§	7,85^*^§	-	-	-	-
	DIG1	Negative regulation of invasive growth	3,74^*^§	1,42^*	3,05^*^§	0,74^*	5,53^*^§	3,24^*^§	10,24^*^§	7,95^*^§
	YGR026W	Uncharacterized	-0,33	0,37	-1,02	-0,32	4,55^*^§	4,24^*^§	-0,24^*	-0,55^*
	SRP40	Preribosome assembly or transport	0,05	0,33	0,32	0,59	2,35^*^§	2,47^*^§	0,59^*	0,71^*
	YAP1802	Endocytosis	6,86	7,37	6,54	7,05	9,59^*^§	11,06^*^§	7,58^*^§	9,05^*^§
	USV1	Putative transcription factor	0,67	-0,13	0,98	0,18	2,36^*^§	3,48^*^§	-1,65^*	-0,53^*
	YBR225W	Uncharacterized	0,32	0,17	0,16	0,00	2,98^*^§	2,11^*^§	2,29^*^§	1,42^*
	YPL260W	Uncharacterized	2,52^*^§	1,46^*	1,89^*^§	0,83^*^§	3,08^*^§	2,45^*^§	1,80^*^§	1,18^*
	SRC1	Linked to TREX	3,25^*^§	1,77^*^§	2,97^*^§	1,49^*	2,66	0,67	2,77	0,79

*statistically significant

^§ log₂ ratio >1.5 (3-fold change)