Table 2.

Effect size of significant GWAS SNPs for ICH volume

Genotyping Information						Discovery (GOCHA Study)			Replication (ESs)			Discovery + Replication Meta - Analysis
SNP	Phenotype	CHR	A1	A2	FRQ A1	Beta	SE	P	Beta	SE	P	Beta	SE	P	P-het
rs11655160	Non-lobar ICH	17	G	A	76%	0.95	0.17	4.33E-08	0.52	0.25	0.036	0.82	0.14	2.5×E-9	0.16
rs9614326	Lobar ICH	22	A	C	97%	1.84	0.32	4.45E-08	0.45	0.66	0.491	1.58	0.29	5.8×E-8	0.06

ESs: European studies; ICH: intracerebral hemorrhage; SE: standard error; A1: tested allele; A2: reference allele; SNP: single nucleotide polymorphism; CHR: chromosome: P-het: study heterogeneity; FRQ: allele frequency