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. Author manuscript; available in PMC: 2018 Aug 9.
Published in final edited form as: Med Image Comput Comput Assist Interv. 2016 Oct 2;9901:79–87. doi: 10.1007/978-3-319-46723-8_10

Algorithm 1.

Semi-supervised hierarchical multimodal feature and sample selection

Input:
Labeled and unlabeled data from MRI and SNP, and the number of hierarchies L.
1: Initialize labeled sample weights in A and feature coefficients in w.
2: for i = 1 to L do
3:  Calculate the data similarity scores in S by Eq. (4).
4:  Calculate the sample weights in  by Eq. (5).
5: repeat
6:   Fix A and solve w in Eq. (6).
7:   Fix w and solve A in Eq. (6).
8: until convergence
9:  Discard insignificant samples and features based on the values in A and w.
10:  Weight the remaining features by the coefficients in w.
11: end for
Output:
Subset of samples and features for classification model training.