Fig. 5.

Effects of SMYD3 on the proliferation-inhibitory, cell-cycle-arrest and apoptosis-stimulating effects of SFN. MGC803 or AGS cells were transfected with SMYD3 and then treated with different concentration of SFN for 48 h. The viability of cells was qualified by MTT assay (A, B), and the cell-cycle distribution (C, D) and apoptosis (E, F) were examined using the flow cytometry analysis. *P < 0.05, **P < 0.01 compared with the corresponding group without SFN treatment (0 μM). #P < 0.05 compared with the corresponding group transfected with empty plasmids (control)