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. 2018 Aug 9;8:11925. doi: 10.1038/s41598-018-30409-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Propensity score-matched cohort study flow chart. S + E indicates individuals treated with simvastatin 20 mg plus ezetimibe 10 mg whereas S indicates those treated with simvastatin 20 mg alone. Of 8,136 subjects, 5,829 subjects without excluding criteria were first stratified by presence of diabetes. Matched S + E and S in the strata of diabetes and no diabetes remained in final analysis.