Figure 4.
Expression of LH2 promotes xenograft tumor growth and metastasis. (A,B) The GATA3 shRNA expressing 344SQ lung cancer cells were stably transfected with empty vector or FLAG-tagged LH2. Each transfectant was subcutaneously injected into the flanks of 8 weeks old 129-elite mice, which were killed at 4 weeks after injection. At necropsy, both subcutaneous xenograft tumors (A) and the lungs (B) were dissected and fixed in formalin.