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. 2018 Aug 9;8:11906. doi: 10.1038/s41598-018-30494-7

Figure 2.

Figure 2

Effect of systemic antibiotic treatment on biofilm production in the 52 ETT-MRSA isolates under O2 or 5% CO2 conditions Median (interquartile range) values for biofilm production of the 52 ETT-MRSA compared with the MRSA-in under O2 (A) and 5% CO2 (B). Time of assessment: day of peak production. Biofilm production was not influenced by systemic treatment with placebo (n = 19), linezolid (n = 11), or vancomycin (n = 22) under either O2 (1.96 [0.61–3.02], 2.30 [0.64–3.83], and 1.49 [0.63–2.67], respectively; p = 0.92) or 5% CO2 (2.02 [1.16–2.34], 1.36 [0.48–2.75], and 1.09 [0.34–2.38], respectively; p = 0.62). Abbreviations: 5% CO2, ambient air with 5% CO2; O2, ambient air; ETT-MRSA, clinical MRSA isolates from endotracheal tubes; MRSA-in, MRSA inoculated into pigs’ lungs; MRSA, methicillin-resistant Staphylococcus aureus.