Table 3.
Interaction analysis between rs3806933 in thymic stromal lymphopoietin and rs6897932 in interleukin 7 receptor under the genotypic model in the combined population.
| Population (n, case/control) | Types | Case (%) | Control (%) | Padj | Odds ratio (95% confidence interval) |
|---|---|---|---|---|---|
| Combined (2,879/3,249) | TT/TT | 24 (0.83) | 8 (0.25) | 6.99 × 10−4 | 4.85 (1.95–12.2) |
| TT/CT | 129 (4.48) | 92 (2.83) | 6.06 × 10−5 | 1.88 (1.38–2.57) | |
| TT/CC | 280 (9.73) | 253 (7.79) | 4.07 × 10−4 | 1.47 (1.19–1.81) | |
| CT/TT | 48 (1.67) | 30 (0.92) | 6.94 × 10−3 | 2.03 (1.21–3.39) | |
| CT/CT | 319 (11.1) | 346 (10.6) | 3.32 × 10−2 | 1.24 (1.02–1.50) | |
| CT/CC | 862 (29.9) | 1,029 (31.7) | 2.92 × 10−2 | 0.86 (0.74–0.98) | |
| CC/TT | 41 (1.42) | 32 (0.98) | 3.50 × 10−2 | 1.73 (1.04–2.87) | |
| CC/CT | 350 (12.2) | 338 (10.4) | 2.68 × 10−4 | 1.43 (1.18–1.74) | |
| CC/CC | 826 (28.7) | 1,121 (34.5) | – | 1 | |
| ADD/ADD | – | – | 5.97 × 10−10 | – |
Padj, P value after adjustment for covariates, such as age, gender, smoking, body mass index, hypertension, diabetes mellitus, total cholesterol, triglyceride, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol; Additive model, rs3806933_CC/CT/TT, rs6897932_CC/CT/TT.