Table 4.
Interaction analysis between rs3806933 in thymic stromal lymphopoietin (TSLP) and rs7025417 in IL33 under the genotypic model in the combined population.
| Population (n, case/control) | Types | Case (%) | Control (%) | Padj | OR (95% CI) |
|---|---|---|---|---|---|
| Combined (1,736/1,093) | TT/TT | 83 (4.78) | 22 (2.01) | 3.67 × 10−4 | 2.98 (1.63–5.43) |
| TT/CT | 132 (7.60) | 61 (5.58) | 1.17 × 10−2 | 1.82 (1.14–2.89) | |
| TT/CC | 40 (2.30) | 27 (2.47) | 6.52 × 10−1 | 0.86 (0.45–1.66) | |
| CT/TT | 232 (13.4) | 106 (9.70) | 9.29 × 10−3 | 1.71 (1.14–2.56) | |
| CT/CT | 373 (21.5) | 283 (25.9) | 4.74 × 10−1 | 0.88 (0.62–1.25) | |
| CT/CC | 111 (6.39) | 79 (7.23) | 1.59 × 10−1 | 0.72 (0.46–1.14) | |
| CC/TT | 222 (12.8) | 104 (9.52) | 3.25 × 10−3 | 1.84 (1.23–2.76) | |
| CC/CT | 426 (24.5) | 306 (28.0) | 2.67 × 10−1 | 0.82 (0.58–1.17) | |
| CC/CC | 117 (6.74) | 105 (9.61) | – | 1 | |
| ADD/ADD | – | – | 1.98 × 10−3 | – |
Padj, P value adjusted for age, gender, body mass index, hypertension, diabetes mellitus, smoking, total cholesterol, triglyceride, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol; OR, odds ratio after the adjustment; CI, confidence interval. Additive model, rs3806933_CC/CT/TT, rs7025417_CC/CT/TT.