Table 2.
Extended-spectrum β-lactamase-producing E. coli isolates from swinein Northwest China.
| Isolate ID | Phylogentic group | Sources | MLST | Resistance profiles | β-lactamase genes | PMQR genes | Virulence genes |
|---|---|---|---|---|---|---|---|
| FF170322 | A | Diarrheal pig | ST10 | AMP AMC EFT CAZ CEX OTC ENR CIP FFC SXT | TEM-1, CTX-M-9, CTX-M-123 | qnrA, qnrB, qepA, oqxAB | estA, astA,F18 |
| JY160633 | A | Healthy pig | ST10 | AMP AMC CAZ ENR CIP FFC OTC GEN | TEM-1, CTX-M-9, CTX-M-123 | qnrS, aac(6')-Ib-cr | estA, F17 |
| FP170743 | A | Diarrheal pig | ST10 | AMP AMC EFT CTX CEX ENR CIP FFC OTC SXT | TEM-1, CTX-M-14, CTX-M-123 | qnrS, qnrA | estB, F18 |
| FP170756 | A | Diarrheal pig | ST10 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-15 | qnrS, qnrA | astA, F5 |
| MX161024 | A | Diarrheal pig | ST10 | AMP AMC EFT CAZ ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-15 | qnrA | astA, F4 |
| HX160912 | A | Diarrheal pig | ST167 | AMP AMC CTX ENR SXT | TEM-1, CTX-M-64 | qnrS, qnrA | estA, F17 |
| JY160509 | A | Healthy pig | ST175 | AMP CTX CEX OTC CAZ GEN SXT | TEM-1,CTX-M-14 | qnrA | estA, F4 |
| FP160935 | A | Healthy pig | ST2715 | AMP AMC CAZ ENR CIP OTC SXT | SHV-12 | - | - |
| JY170618 | A | Diarrheal pig | ST5236 | AMP AMC CTX CAZ FFC GEN AMK OTC | TEM-1, CTX-M-14 | qnrA | estA, F18 |
| HX160826 | B1 | Diarrheal pig | ST75 | AMP CAZ CEX ENR FFC OTC | TEM-1, CTX-M-14 | qnrS | estA, F17 |
| ZZ160931 | B1 | Healthy pig | ST155 | AMP AMC CTX CAZ OTC GEN AMK SXT | TEM-1, CTX-M-64 | - | - |
| ZZ170521 | B1 | Diarrheal pig | ST183 | AMP AMC CTX CAZ ENR OTC SXT | TEM-1, CTX-M-14 | qnrA | estA, astA, F6 |
| FP170723 | B1 | Healthy pig | ST302 | AMC CAZ OTC ENR FFC | CTX-M-123 | - | - |
| JY170327 | B1 | Diarrheal pig | ST355 | AMP CAZ OTC ENR SXT | TEM-1, CTX-M-14 | qnrS | eae |
| FF170327 | B1 | Healthy pig | ST443 | AMP AMC CAZ CEX ENR OTC SXT | CTX-M-14 | qnrS, aac(6')-Ib-cr | astA |
| HX161021 | B2 | Diarrheal pig | ST29 | AMP AMC EFT CTX CAZ ENR CIP FFC OTC GEN AMK SXT | CTX-M-14, CTX-M-123 | qnrB, aac(6')-Ib-cr | estA, F4 |
| FF170425 | B2 | Diarrheal pig | ST95 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-15, CTX-M-64 | - | astA, F18 |
| MX160918 | B2 | Diarrheal pig | ST104 | AMP AMC EFT CTX CEX OTC ENR CIP FFC GEN AMK SXT | TEM-1, CTX-M-64 | qnrS, aac(6')-Ib-cr | astA, estA, F4 |
| JY160522 | B2 | Diarrheal pig | ST104 | AMP AMC EFT CTX CAZ OTC ENR CIP FFC GEN AMK SXT | TEM-1, CTX-M-64 | qnrS, aac(6')-Ib-cr | estA, F4, F18 |
| HX160809 | B2 | Diarrheal pig | ST127 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-123 | qnrS | estB, F6 |
| FP170708 | B2 | Diarrheal pig | ST127 | AMP AMC EFT CTX CEX ENR CIP FFC OTC GEN AMK SXT | CTX-M-123 | - | estB, F5 |
| JY160503 | B2 | Diarrheal pig | ST131 | AMP AMC EFT CTX CAZ CEX MEM ENR CIP FFC OTC GEN AMK SXT | CTX-M-9, CTX-M-14, CTX-M-64, KPC-2, OXA-48 | qnrS, qnrB, qnrD, aac(6')-Ib-cr, qepA | elt, estA, F6 |
| MX150822 | B2 | Diarrheal pig | ST278 | AMP AMC EFT CTX CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-14 | qnrS | astA, estB, F4 |
| FF170416 | B2 | Diarrheal pig | ST355 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | SHV-2, CTX-M-64 | qnrB | estA, F4 |
| FF170325 | B2 | Diarrheal pig | ST372 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-14, CTX-M-15, CTX-M-64 | qnrS, aac(6')-Ib-cr | estB, F4, F18 |
| FF170316 | B2 | Diarrheal pig | ST372 | AMP AMC EFT CTX CAZ ENR CIP FFC OTC GEN AMK SXT | CTX-M-14, CTX-M-15, CTX-M-123 | qnrS, aac(6')-Ib-cr | elt, estA, F4 |
| MX150923 | C | Diarrheal pig | ST23 | AMP AMC CTX CAZ EFT CEX ENR FFC GEN AMK SXT | TEM-1, CTX-M-14 | qnrS, qnrA | estA, estB, F18 |
| MX150814 | C | Diarrheal pig | ST23 | AMP AMC EFT CTX CAZ ENR CIP OTC GEN AMK SXT | TEM-1, CTX-M-14 | qnrB, aac(6')-Ib-cr | elt, F4 |
| ZZ160815 | C | Diarrheal pig | ST23 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN SXT | TEM-1, CTX-M-14 | qnrS | estA, F18 |
| JY160518 | D | Diarrheal pig | ST38 | AMP AMC EFT CTX CAZ CEX MEM ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-15, OXA-48 | qnrS, qnrA | elt, estB, F4 |
| HX160976 | D | Diarrheal pig | ST38 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | CTX-M-9, CTX-M-14 | qnrA | elt, estB, F41 |
| HX160944 | D | Diarrheal pig | ST38 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | CTX-M-9,CTX-M-14, CTX-M-64 | qnrB | elt, astA, F4 |
| HX161006 | D | Diarrheal pig | ST69 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-14 | qnrS, qnrA | astA, F5 |
| MX150820 | D | Diarrheal pig | ST405 | AMP AMC EFT CTX CAZ CEX MEM ENR CIP FFC OTC GEN AMK SXT | SHV-12, CTX-M-14, CTX-M-15, NDM-1 | qnrB, aac(6')-Ib-cr | elt, estA, F4 |
| LZ161015 | D | Diarrheal pig | ST405 | AMP AMC EFT CTX CAZ ENR CIP FFC OTC GEN AMK SXT | SHV-12, CTX-M-15 | qnrS, qnrB | estB, F4 |
| JC160611 | D | Diarrheal pig | ST405 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-9, KPC-2 | qnrS, qnrB | estB, F4 |
| JY160512 | D | Diarrheal pig | ST405 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT CLT | TEM-1, CTX-M-9, CTX-M-14, CTX-M-15 | qnrA, qnrD, oqxAB | elt, estA, F4 |
| FP170711 | D | Diarrheal pig | ST405 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, SHV-12, CTX-M-15, OXA-48 | aac(6')-Ib-cr, oqxAB | elt, estB, F4 |
| HX170832 | D | Diarrheal pig | ST405 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, SHV-12, CTX-M-15, OXA-48 | aac(6')-Ib-cr | elt, estB, F4 |
| SY160832 | D | Diarrheal pig | ST648 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | SHV-2, CTX-M-9, CTX-M-14, CTX-M-123 | qnrA, aac(6')-Ib-cr | estB, astA, F17 |
| ZZ160908 | D | Diarrheal pig | ST648 | AMP AMC EFT CTX CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-9, CTX-M-14, CTX-M-15 | qnrA | estB, astA, F41 |
| ZZ160917 | D | Diarrheal pig | ST648 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-14, CTX-M-15, CTX-M-64 | qnrS | estA, F18 |
| JY160865 | D | Diarrheal pig | ST648 | AMP AMC EFT CTX CAZ CEX ENR CIP FFC OTC GEN AMK SXT | TEM-1, CTX-M-14, CTX-M-15, CTX-M-64 | qnrS | estB, F18 |
| FP170733 | E | Diarrheal pig | ST350 | AMP AMC CTX CEX ENR OTC SXT | CTX-M-9 | qnrS | eae |
AMP, ampicillin; AMC, amoxicillin-clavulanic acid; EFT, ceftiofur; CTX, cefotaxime; CAZ, ceftazidime; CEX, ceftriaxone; MEM, meropenem; ENR, enrofloxacin; CIP, ciprofloxacin; FFC, florfenicol, OTC, oxytetracycline; GEN, gentamicin; AMK, amikacin; SXT, sulfamethoxazole-trimethoprim; CLT, colistin.