Table 7.
Sensitivity and specificity of the ALS chromosome conformation signature (CCS) when used to classify a set of clinical samples (n = 74) taken from two ALS clinical trials.
| Statistic | Value | 95% Cl |
|---|---|---|
| Sensitivity | 0.8333 | 51.59% to 97.91% |
| Specificity | 0.7692 | 46.19% to 94.96% |
| Positive likelihood ratio | 3.61 | 1.30 to 10.06 |
| Negative likelihood ratio | 0.22 | 0.06 to 0.79 |
| Disease prevalence | 48% (*) | 27.80% to 68.69% |
| Positive predictive value | 76.92% (*) | 46.19% to 94.96% |
| Negative predictive value | 83.33% (*) | 51.59% to 97.91% |
Abbreviations. 95% CI: 95% confidence interval.