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Post-transcriptional regulation of inflammation-related mRNAs by RBPs. Regulatory RBPs target the 3′ UTRs of mRNAs to repress expression of the target transcript. AREs and stem-loop structures in 3′ UTRs are well-studied cis-elements recognized by a set of RBPs for controlling the stability of target mRNAs. Whereas TTP, AUF1 and HuR recognize AREs, Regnase-1, Roquin and Arid5a bind to stem-loop structures. CDS, coding sequence.
