Table 1.

MicroRNAs regulating microglia activation and their gene targets.

Function	miRNA	Gene target	Reference
Negative regulator of microglial pro-inflammatory activation	miR-7	NLRP3	Zhou Y. et al., 2016
	miR-26a	ATF2	Kumar et al., 2015
	miR-27a	TLR4, IRAK4	Lv et al., 2017
	miR-30a	NEUROD1	Fu et al., 2018
	miR-93		Tian et al., 2017
	miR-124	RFX1	Dong et al., 2016; Guo et al., 2016; Hamzei Taj et al., 2016a; Feng et al., 2017; Cunha et al., 2018
	miR-125b	STAT3	Parisi et al., 2013; Cunha et al., 2018
	miR-128		Yang et al., 2017
	miR-145	PLA2G4A	Qi et al., 2017
	miR-146a		Sharma et al., 2015; Zhou et al., 2015; Zhao et al., 2016; Deng et al., 2017; Cunha et al., 2018
	miR-181c	MLL1	Ma et al., 2016; Yin M. et al., 2017
	miR-199b	IKKβ	Zhou et al., 2016
	miR-200b	JUN	Jadhav et al., 2014
	miR-203	MYD88	Yang et al., 2015
	miR-339	IKKβ, IKKe	Zhang et al., 2014
	miR-365	IL6	Parisi et al., 2013
	miR-367	IRAK4	Yuan et al., 2015
	miR-424	CDC25A, CCND1, CDK6	Zhao et al., 2013; Liu et al., 2015
	miR-Let-7a		Cho K.J. et al., 2015
	miR-Let-7c	CASP3	Lv et al., 2018
Positive regulator of microglial pro-inflammatory activation	miR-9	MCPIP1	Yao et al., 2014
	miR-29b	TNFAIP3	Thounaojam et al., 2014
	miR-145	NR4A2	Xie et al., 2017
	miR-155	RACK1, SOCS-1	Cardoso et al., 2012; Butovsky et al., 2015; Woodbury et al., 2015; Yin H. et al., 2017
	miR-195	ATG14	Shi et al., 2013
	miR-204	SIRT1	Li et al., 2015
	miR-206	IGF1	Xing et al., 2016
	miR-221	SOCS1	Xia et al., 2016
	miR-7116	TNFα	He et al., 2017
Positive regulator of microglial anti-inflammatory activation	miR-124	RAC1	Brennan et al., 2016; Hamzei Taj et al., 2016b; Louw et al., 2016; Svahn et al., 2016
	miR-Let-7a		Song et al., 2015
	miR-Let-7c	CASP3	Ni et al., 2015