Table 3.
Summary of local tumor control and 1-year mortality in the unmatched and matched cohort in all patients and stratified in BCLC B and C
| Unmatched cohort | Matched cohort | |||||
|---|---|---|---|---|---|---|
| TACE | SBRT | p value | TACE | SBRT | p value | |
| All patients | n = 367 | n = 35 | n = 70 | n = 35 | ||
| Target lesions | 367 | 46 | 70 | 46 | ||
| Local tumor controlb n (%) [95%CI] |
273 (74.4) [70.0–79.0]a |
39 (84.8) [71.9–96.9] |
0.146 | 58 (82.9) [74.3–91.4] |
39 (84.8) [71.9–96.9] |
0.805 |
| 1-year-mortality n (%) [95%CI] |
141 (38.4) [33.8–43.6] |
17 (53.1) [37.5–71.9] |
0.073 | 37 (52.9) [40.0–64.3] |
17 (53.1) [37.5–68.8] |
0.989 |
| BCLC B | n = 29 | n = 24 | n = 49 | n = 24 | ||
| Target lesions | 299 | 23 | 49 | 23 | ||
| Local tumor control n (%) [95%CI] |
225 (75.3) [70.6–80.2] |
19 (82.6) [66.7–95.8] |
0.612 | 41 (83.7) [72.3–93.5] |
19 (82.6) [66.7–95.8] |
0.847 |
| 1-year-mortality n (%) [95%CI] |
100 (33.4) [28.1–39.1] |
11 [45.8) [30.0–71.4] |
0.120 | 20 (40.8) [26.9–55.0] |
11 (45.8) [29.2–70.8] |
0.616 |
| BCLC C | n = 68 | n = 11 | n = 21 | n = 11 | ||
| Target lesions | 68 | 23 | 21 | 23 | ||
| Local tumor control n (%) [95%CI] |
48 (70.6) [60.0–81.0] |
20 (87.0) [72.2–100] |
0.272 | 17 (81.0) [64.0–95.8] |
20 (87.0) [72.2–100] |
0.648 |
| 1-year-mortality n (%) [95%CI] |
41 (60.3) [48.3–70.9] |
6 (5.4) [27.3–90.0] |
0.999 | 17 (81.0) [64.0–95.8] |
6 (5.4) [27.3–90.0] |
0.397 |
a95%CI refers to the relative percentages
bLocal tumor control refers to the treated target lesions