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. 2018 Aug 3;9:848. doi: 10.3389/fphar.2018.00848

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Copyright © 2018 Bader, Jügelt, Schultz and Schroeder.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Influence of 100 nM Aβ42 and combination of Aβ42 + 20 μg/ml Ginkgo medications on regularity of cortex network activity in vitro. Acute addition of Aβ42 induces measurable activity changes of spike contrast SD, burst area SD and burst duration CVtime reflecting the variation over time as an indicator for regularity. DMSO control, Aβ42 + DMSO, Aβ42 + Tebonin, Aβ42 + Ginkgo B, Aβ42 + Ginkgo C, Aβ42 + Ginkgo D, Aβ42 + Ginkgo E, Aβ42 + Ginkgo F. Shown are mean values ± standard error, normalized to native activity. Student's t-test with Bonferroni-Holm correction with *p ≤ 0.05.