Table 1.

Demographic characteristics of discovery and validation cohort samples

Study subjects	Discovery cohort: 48 (24 paired) samples	Validation cohort: 30 (15 paired) samples
Mean age (in years)	37.94 (SD = 14.24) (range 12–74)	39.83 (SD = 10.77) (range 22–60)
Mean age of onset (in years)	33.17 (SD = 14.03) (range 10–73)	33.12 (SD = 11.21) (range 9–52)
Type I–type II	19–5	10–5
Type I–type II: age distribution	Mean age/onset 32.4/28.3	Mean age/onset 34.05/26.83
	Mean age/onset 54/51.5	Mean age/onset 51.4/45.7
Sex distribution	18 males, 6 females	10 males, 5 females