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. 2001 Oct 30;98(23):13255–13260. doi: 10.1073/pnas.231326898

Figure 2.

Figure 2

Specificity of T cells from donor 6947 for p538. (a) Peptide-specific proliferation of bulk culture 6947 against autologous PBMCs pulsed with TGFβRII frameshift peptides. (b) Peptide-specific proliferation of the TLC 6947-22 against the p538 peptide. Autologous B-LCLs (6947 EB) were used as APCs. (c) Blocking of the TGFβRII specific response by anti-HLA-DP mAb. (d) Panel studies using homozygous B-LCLs corresponding to DPB1 alleles of donor 6947. Solid bars, APC + p538; open bars, APC − p538. The HLA-DPB1 type of the different B-LCLs was 6947; EB: DPB1*0301, 9097: DPB1*0301/0401, 9031: DPB1*0401, 9009: DPB1*0401/1401.