Table 2.
Overview of all immune cell analyses between high (HMD) and low (LMD) density breast samples
| Epithelium | Difference (p value) | Stroma | Difference (p value) | |||
|---|---|---|---|---|---|---|
| Marker | HMD | LMD | HMD | LMD | ||
| CD68 | 5.61 (0.61) | 2.56 (0.75) | p =0.004 | 4.72 (0.9) | 3.14 (0.98) | p=0.15 |
| CD11c | 1.53 (0.36) | 0.5 (0.22) | p =0.02 | 5.30 (1.06) | 2.16 (0.80) | p =0.03 |
| CD56 | 5.30 (1.41) | 2.29 (0.73) | p=0.07 | 1.81 (0.74) | 0.92 (0.36) | p=0.31 |
| CD20 | 1.93 (0.52) | 0.31 (0.15) | p =0.0039 | 5.35 (2.03) | 1.50 (0.59) | p=0.28 |
| CD4 | 20.47 (2.69) | 15.07 (2.55) | p=0.05 | 21.42 (2.63) | 15.95 (2.64) | p =0.04 |
| CD8 | 6.69 (1.43) | 4.82 (1.75) | p=0.22 | 3.49 (0.83) | 2.18 (0.66) | p=0.15 |
| PD1 | 2.79 (0.52) | 1.25 (0.35) | p =0.02 | 1.45 (0.46) | 0.29 (0.20) | p =0.04 |
| IL-6 | 24.68 (4.13) | 18.34 (5.80) | p =0.03 | 21.07 (5.53) | 11.24 (3.98) | p =0.006 |
| IL-4 | 23.94 (5.19) | 16.04 (3.60) | p=0.09 | 4.41 (1.29) | 1.28 (0.59) | p =0.04 |
| IFNγ | 4.66 (0.88) | 2.22 (0.80) | p=0.06 | 1.41 (0.69) | 0.67 (0.36) | p=0.56 |
Data are presented as the Mean+/- (SEM) percentage of immune + cells (ie: CD68) as a function of total epithelial cell nuclei counted in 4 random areas within each tissue sample. Data with significant differences p<0.05 are highlighted bold. N=10-15 women