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. 2018 May 7;99(1):65–72. doi: 10.4269/ajtmh.17-0434

Figure 3.

Figure 3.

Comparison of the mean (SEM) inhibitory dilution (ID50: number of dilutions of plasma sample that produces a 50% inhibition of hypoxanthine uptake into malaria parasites compared to drug-free plasma control samples) of plasma samples obtained from seven healthy Vietnamese volunteers who were administered on separate occasions a 3-day course of the artemisinin combination therapies (ACT) [artesunate-amodiaquine (Coarsucam) or artemisinin-piperaquine (Artequick)] against the drug-sensitive D6 Plasmodium falciparum line. The difference between the two treatments is statistically significant P < 0.05 for the time points from 48.25 to 51 hours (inclusive) and not statistically significant for all other time points.