FIGURE 5:

The Kazal-like motif domain is important for short RECK binding to long RECK. (A) Schematic depiction of the structure of the short RECK isoform conjugated to Flag and versions of the long RECK isoform with domain-specific deletions constructed for coimmunoprecipitation. (B) Results from a coimmunoprecipitation experiment with the constructs shown in A. Input samples are shown at the bottom. Short RECK–long RECK interaction was reduced when the domain containing the Kazal-like motif was deleted (∆635-773).