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Aβ42 oligomers change the phosphorylation of tau epitopes. (A) Western blotting on whole cell extracts showing the levels of Tau Thr231 (P-Tau), Tau-1 (nP-Tau) and total tau (T-Tau) following Aβ administration. Normalized to β-actin. Immunofluorescence labeling indicating the presence of nuclear phosphorylated tau (Bi), which significantly decreases following the Aβ treatment, without changes in total nuclear tau (Bii) or nuclear nP-Tau (C). N = 5. ∗P < 0.05.
