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Aβ42 oligomers alter nucleolar tau localization 24 h post-incubation. Immunofluorescence labeling in buffer-treated cells show co-localization between nP-Tau and FBL (A). 10 μM Aβ42 treatment induces the delocalization of nP-Tau from FBL (B). Quantification showed that this altered colocalization is associated with a significant reduction in the nucleolar nP-Tau (C) N = 5. ∗P < 0.05.
