Fig. 5.
Characterization of gossypolone-liposomes (Gn-lip). a TEM image (left), size distribution (upper right), and Zeta-potential (lower right) of blank liposomes. b TEM image (left), size distribution (upper right), and Zeta-potential (lower right) of Gn-loaded liposomes. c MTT-based cytotoxicity assay of free Gn, encapsulated Gn (Gn-lip), and the liposomes with the same concentrations of vehicle in Gn-lip using selected colon cancer cell lines (n = 3). Gn-lip and Gn showed similar cell viability profiles; while the liposomes alone did not show evident cytotoxicity within the investigated concentrations