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. Author manuscript; available in PMC: 2018 Aug 10.
Published in final edited form as: Synapse. 2017 Feb 11;71(5):10.1002/syn.21962. doi: 10.1002/syn.21962

FIGURE 4.

FIGURE 4

Blocking eCB transport unmasks BDNF-induced potentiation in somatosensory cortex. (a) Representative traces of mEPSCs during baseline in the presence of intracellular AM404 (5 μM) and during bath-applied BDNF (0.8 nM) in the presence of intracellular AM404. Scale bar 10 pA, 100 ms. (b) Group time courses showing the effect of bath-applied BDNF (0.8 nM) in the presence of intracellular AM404 on mEPSC frequency (top) and amplitude (bottom). (c) Data from individual experiments showing a statistically significant increase in mEPSC frequency during minutes 3–5 of BDNF exposure in the presence of internal AM404. *p < .03 compared to baseline