Fig. 2.

Optical and photoacoustic characterization and WM-266 cells interaction. A) Absorbance (continuous line) and photoacoustic normalized spectra (dashed line) of ICG and ICG-RGD in glucose solution 5.5% (left) and albumin bound (right); B) Photoacoustic signal at maximum wavelength measured in glucose solution (left panel) and in human serum, after 1 h incubation at RT (right panel). C) Representative optical image (left) and quantification (right) of WM-266 cells interaction after incubation for 30 min with 1 μM of either ICG or ICG-RGD, with or without co-incubation with 100 μM of the unlabelled peptide c(RGDfK). *P < 0.0001, 1-way ANOVA followed by Bonferroni post-hoc test.