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Effects of deletion of aspf1 and/or gliP on the virulence of A. fumigatus. Mice were immunosuppressed with cortisone acetate, infected with an aerosol of the indicated strains of A. fumigatus, and monitored for survival. Data are the combined results of two independent experiments for a total 16 mice per strain. *P < 0.001 compared to Af293 and the Δaspf1+ aspf1 complemented strain; †p < 0.01 compared to the Δglip and Δaspf1 mutants by the log-rank test.
