Table 1.

A. fumigatus genes that were differentially expressed in the ΔgliP mutant relative to the wild-type strain at 5 days post-infection in the lungs of immunosuppressed mice. These results are based on nanoString probe counts (Table S1). Data are the mean of 3 biological replicates.

Gene	Gene Name	Putative Function	ΔgliP/WT
Afu5g02330	aspf1	Cell surface – allergen, cytotoxin, upregulated in biofilm and in vivo	6.8
Afu3g12890	hasA	Transcription factor – regulates biosynthesis of hexadehydroastechrome	5.1
Afu1g01550	zrfA	Zinc transporter – acidic environments	3.8
Afu4g14070		Cell surface – secreted protein, glycosyl transferase	2.3
Afu5g14800		Metabolism – lactate dehydrogenase, downregulated in biofilm	2.2
Afu4g09560	zrfC	Zinc transporter – neutral or alkaline environments	2.1
Afu4g09580	aspf2	Cell surface – fibrinogen binding protein, required for growth in zinc-limited conditions	2.1
Afu1g14560	msdS	Putative 1,2-α-mannosidase; secreted protein; fibrinogen-binding	0.43
Afu6g03540	acuE	Metabolism – malate synthase, glyoxylate cycle	0.39
Afu2g12850	gel3	Putative GPI anchored β(1–3)glucanosyltransferase	0.34
Afu8g01310		Iron acquisition – metalloreductase	0.15
Afu4g11800	alp1	Cell surface – secreted protein alkaline serine protease	0.13
Afu6g09660	gliP	Gliotoxin – non-ribosomal peptide synthetase	0.03