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. Author manuscript; available in PMC: 2018 Aug 10.
Published in final edited form as: Oncogene. 2016 Apr 4;35(40):5295–5303. doi: 10.1038/onc.2016.70

Figure 5. Autophagy promotes survival upon BRAFV600/MAPK inhibition.

Figure 5.

YUSIV BRAFwt melanoma cells treated with 10 nM AS703026 with or without 1 mM AICAR for 72 h. Left—Cells remaining attached to the plate were fixed and DAPI stained to visualize the surviving population for (a) shCntrl, (b) shATG5–1 and (c) shATG5–2. Right—Data represent mean±s.e.m. across at least four different fields of view. ***P<0.001; ns, not significant.