Table 1.
Transcripts showing strong differential expression in DRG
| Gene symbol | Gene name | DRG RPKM | Sciatic RPKM | Fold DRG enriched |
|---|---|---|---|---|
| Cytoskeleton | ||||
| Nefl | Neurofilament, light polypeptide | 3773.2 | 3.0 | 1202.1 |
| Nefm | Neurofilament, medium polypeptide | 3463.1 | 2.7 | 1229.3 |
| Nefh | Neurofilament, heavy polypeptide | 1605.7 | 0.7 | 2049.0 |
| Tubb3 | Tubulin, beta 3 | 1224.0 | 8.7 | 138.8 |
| Stmn2 | Stathmin-like 2 | 929.9 | 7.8 | 118.0 |
| Prph | Peripherin | 810.3 | 4.8 | 165.2 |
| Stmn3 | Stathmin-like 3 | 444.7 | 7.8 | 56.1 |
| Avil | Advillin | 215.5 | 1.4 | 142.6 |
| Tuba4a | Tubulin, alpha 4a | 204.2 | 2.6 | 74.4 |
| Vesicles, SNARE, fusion | ||||
| Snap25 | Synaptosomal-associated protein, 25kDa | 741.7 | 1.3 | 535.8 |
| Cplx1 | Complexin 1 | 296.3 | 0.8 | 337.2 |
| Syp | Synaptophysin | 208.5 | 0.5 | 328.6 |
| Sv2c | Synaptic vesicle glycoprotein 2C | 122.1 | 0.5 | 211.1 |
| Rph3a | Rabphilin 3A homolog | 117.8 | 0.2 | 460.3 |
| Synpr | Synaptoporin | 97.1 | 0.1 | 423.5 |
| Slc17a7 | Solute carrier family 17, member 7 | 92.2 | 0.0 | 793.8 |
| Syt2 | Synaptotagmin II | 91.4 | 0.0 | 632.9 |
| Cadps | Calcium-dependent secretion activator | 84.2 | 0.3 | 215.1 |
| Ap3b2 | Adaptor-related protein complex 3, beta 2 subunit | 72.3 | 0.4 | 139.7 |
| Syt4 | Synaptotagmin IV | 66.0 | 0.2 | 228.9 |
| Stx1b | Syntaxin 1B | 65.6 | 0.8 | 75.1 |
| Syn1 | Synapsin I | 55.9 | 0.7 | 73.8 |
| Slc17a6 | Solute carrier family 17, member 6 | 28.1 | 0.0 | 261.2 |
| Stxbp5l | Syntaxin binding protein 5-like | 6.2 | 0.0 | 57.6 |
| Peptides/chaperones/granins | ||||
| Calca | Calcitonin-related polypeptide alpha | 605.1 | 0.5 | 982.5 |
| Tac1 | Tachykinin, precursor 1 | 182.7 | 0.2 | 674.3 |
| Scg5 | Secretogranin V (7B2) | 115.6 | 0.6 | 170.7 |
| Scg2 | Secretogranin II | 110.6 | 0.1 | 446.3 |
| Calcb | Calcitonin-related polypeptide beta | 86.4 | 0.2 | 337.0 |
| Chgb | Chromogranin B | 84.3 | 0.1 | 375.7 |
| Chga | Chromogranin A | 60.5 | 0.2 | 173.5 |
| Sst | Somatostatin | 39.1 | 0.1 | 189.9 |
| Channels and pumps | ||||
| Atp1b1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 520.8 | 5.0 | 101.3 |
| Atp1a3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide | 142.4 | 0.2 | 498.9 |
| Scn4b | Sodium channel, voltage-gated, type IV, beta | 129.4 | 0.1 | 557.5 |
| Kcnab2 | Potassium voltage-gated channel, shake-related subfamily, beta member 2 | 122.4 | 2.2 | 53.0 |
| P2rx3 | Purinergic receptor P2X, ligand-gated ion channel, 3 | 85.0 | 0.5 | 135.6 |
| Scn10a | Sodium channel, voltage-gated, type X, alpha subunit | 79.2 | 0.0 | 732.6 |
| Glrb | Glycine receptor, beta | 78.1 | 0.2 | 298.7 |
| Gabrg2 | Gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 66.9 | 0.1 | 432.5 |
| Slc24a2 | Solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 | 66.5 | 0.9 | 64.7 |
| Gabra2 | Gamma-aminobutyric acid (GABA) A receptor, alpha 2 | 62.1 | 0.1 | 260.1 |
| Scn11a | Sodium channel, voltage-gated, type XI, alpha subunit | 59.5 | 0.0 | 516.5 |
| Cacng7 | Calcium channel, voltage-dependent, gamma subunit 7 | 45.6 | 0.2 | 148.2 |
| Scn8a | Sodium channel, voltage gated, type VIII, alpha subunit | 37.6 | 0.2 | 124.7 |
| Gabrg1 | Gamma-aminobutyric acid (GABA) A receptor, gamma 1 | 29.4 | 0.0 | 244.9 |
| Grin1 | Glutamate receptor, ionotropic, N-methyl D-aspartate 1 | 22.1 | 0.1 | 138.3 |
| Gabrb3 | Gamma-aminobutyric acid (GABA) A receptor, beta 3 | 21.9 | 0.1 | 129.4 |
| Growth factors/receptors/transcriptional reg | ||||
| Fgf13 | Fibroblast growth factor 13 | 178.0 | 0.7 | 209.9 |
| Ngfr | Nerve growth factor receptor (TNFR superfamily, member 16) | 170.9 | 3.0 | 54.6 |
| Zcchc18 | Zinc finger, CCHC domain containing 18 | 94.6 | 1.4 | 64.1 |
| Tagln3 | Transgelin 3 | 80.6 | 0.7 | 102.7 |
| Dner | Delta/notch-like EGF repeat containing | 74.1 | 0.6 | 106.3 |
| Bex2 | Brain expressed X-inked 2 | 72.9 | 0.8 | 83.2 |
| Ntrk1 | Neurotrophic tyrosine kinase, receptor, type 1 | 65.1 | 0.3 | 158.2 |