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. 2018 Jul 25;53(4):1481–1492. doi: 10.3892/ijo.2018.4502

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Copyright: © Huang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of TCTP on the expression of HMGB1 in xenograft tumors in nude mice. (A) Expression of TCTP and HMGB1 in the developed tumors in the nude mouse spleen were detected 5 weeks following inoculation with LoVo cells (magnification, ×400). ^*P<0.05, compared with mice receiving normal control LoVo cells. (B) Expression of TCTP and HMGB1 in metastatic tumors in the nude mouse liver were detected 5 weeks following inoculation with LoVo cells (magnification, ×400). ^*P<0.05, compared with mice receiving normal control LoVo cells. The H&E panel shows sections of liver stained with H&E (magnification, ×100). TCTP-NC, normal control LoVo cells; TCTP-K, LoVo cells transfected with TCTP-knockdown vector; TCTP-O, LoVo cells transfected with TCTP-overexpression vector; TCTP, translationally controlled tumor protein; HMGB1, high mobility group box 1; H&E, hematoxylin and eosin.