Table III.
The top ten most significant items of Gene Ontology (GO) terms of the co-expression genes of homeobox A3 (HOXA3) in non-small cell lung cancer.
| Category | Term | Count | P-value | FDR |
|---|---|---|---|---|
| Biological processes | ||||
| GOTERM_BP_FAT | GO:0048706~embryonic skeletal system development | 8 | 3.41E-05 | 0.06 |
| GOTERM_BP_FAT | GO:0001501~skeletal system development | 14 | 1.07E-04 | 0.18 |
| GOTERM_BP_FAT | GO:0045682~regulation of epidermis development | 5 | 1.17E-04 | 0.19 |
| GOTERM_BP_FAT | GO:0030334~regulation of cell migration | 10 | 1.80E-04 | 0.30 |
| GOTERM_BP_FAT | GO:0042981~regulation of apoptosis | 23 | 1.97E-04 | 0.33 |
| GOTERM_BP_FAT | GO:0043067~regulation of programmed cell death | 23 | 2.27E-04 | 0.38 |
| GOTERM_BP_FAT | GO:0010941~regulation of cell death | 23 | 2.39E-04 | 0.40 |
| GOTERM_BP_FAT | GO:0048705~skeletal system morphogenesis | 8 | 3.64E-04 | 0.60 |
| GOTERM_BP_FAT | GO:0040012~regulation of locomotion | 10 | 4.64E-04 | 0.77 |
| GOTERM_BP_FAT | GO:0051270~regulation of cell motion | 10 | 4.81E-04 | 0.80 |
| Cellular components | ||||
| GOTERM_CC_FAT | GO:0005626~insoluble fraction | 22 | 0.000184 | 0.24 |
| GOTERM_CC_FAT | GO:0005624~membrane fraction | 20 | 0.000837 | 1.07 |
| GOTERM_CC_FAT | GO:0031012~extracellular matrix | 12 | 0.001071 | 1.37 |
| GOTERM_CC_FAT | GO:0044420~extracellular matrix part | 7 | 0.001490 | 1.90 |
| GOTERM_CC_FAT | GO:0045177~apical part of cell | 8 | 0.002892 | 3.66 |
| GOTERM_CC_FAT | GO:0000267~cell fraction | 22 | 0.004675 | 5.86 |
| GOTERM_CC_FAT | GO:0042995~cell projection | 16 | 0.006747 | 8.35 |
| GOTERM_CC_FAT | GO:0005578~proteinaceous extracellular matrix | 10 | 0.006859 | 8.48 |
| GOTERM_CC_FAT | GO:0016324~apical plasma membrane | 6 | 0.013372 | 15.92 |
| GOTERM_CC_FAT | GO:0016323~basolateral plasma membrane | 7 | 0.020688 | 23.61 |
| Molecular functional | ||||
| GOTERM_MF_FAT | GO:0043565~sequence-specific DNA binding | 20 | 0.000041 | 0.06 |
| GOTERM_MF_FAT | GO:0008047~enzyme activator activity | 11 | 0.004149 | 5.55 |
| GOTERM_MF_FAT | GO:0005547~phosphatidylinositol-3,4,5-trisphosphate binding | 3 | 0.004179 | 5.59 |
| GOTERM_MF_FAT | GO:0016641~oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | 3 | 0.010187 | 13.11 |
| GOTERM_MF_FAT | GO:0030695~GTPase regulator activity | 11 | 0.014540 | 18.21 |
| GOTERM_MF_FAT | GO:0016638~oxidoreductase activity, acting on the CH-NH2 group of donors | 3 | 0.016640 | 20.58 |
| GOTERM_MF_FAT | GO:0060589~nucleoside-triphosphatase regulator activity | 11 | 0.016712 | 20.66 |
| GOTERM_MF_FAT | GO:0035091~phosphoinositide binding | 5 | 0.025094 | 29.45 |
| GOTERM_MF_FAT | GO:0016208~AMP binding | 3 | 0.028747 | 33.00 |
| GOTERM_MF_FAT | GO:0003779~actin binding | 9 | 0.028844 | 33.09 |