(a) The interface region between the α and β subunits, with the boxed area enlarged in panels b-f and the viewing angle indicated by an arrow, the region with fenestration between the subunits is marked with an asterisk. The α and α* subunits are colored in salmon, β and β* are colored in lime, and γ is colored in marine and shown as cartoon. Side chains for amino acids for which specific interactions were observed are shown with interactions depicted in dashed lines. In (b) is the α(+)/β(-) interface, (c) the β(+)/α*(-) the interface, (d) the α*(+)/γ(-) interface, (e) the γ(+)/β*(-) interface and (f) the β*(-)/α(-) interface.