Table 1.

Fold change in the detection of four viruses by total nucleic acid extraction methods compared to QIAamp^® MinElute^® Virus Spin kit

Sample extraction method	Detection of EBV	Detection of FeLV	Detection of Reo3	Detection of RSV
Invitrogen PureLink™a	−1.55	1.68	7.89	2.31
QIAGEN Circulating Nucleic Acida	−1.27	−2.50	−1.72	−1.32
Clonetech Nucleospin®a	−15.46	−62.25	−1.18	−8.00
Invitrogen Dynabeads®b	−1.02	1.22	−1.01	1.23
Perkin Elmer Chemagic™b	−1.49	−2.66	−5.54	−3.39
Phenol:Chloroformc	−27.86	−30.06	−7.52	−8.75
Acid phenol:chloroformc	−7.94	−3.36	9.58	1.69

Sample extraction methods were assessed for their efficient extraction of four representative viruses. Silica membrane column- (a), magnetic bead- (b), and precipitation (c)-based extractions were included