Table 1.

Clinical and molecular characteristics of primary human AML samples analyzed in Fig. 6g

Sample	SU050	SU227	SU369	SU416	SU444	SU540
Age	50	30	86	67	60	68
Gender	Male	Male	Male	Female	Male	Female
Primary/secondary	Primary	Primary	Primary	Secondary	Primary	Primary
De novo/relapsed	Relapsed	De novo	De novo	De novo	De novo	De novo
Cytogenetics	Normal	Normal	48XY,+mar[3]	Normal	Normal	Normal
FLT3-ITD	Positive	Positive	Negative	Positive	Positive	Positive
%CD34	<1%	65%	<1%	6%	3%	34%
WHO classification	AML with multilineage dysplasia without Antecede	AML with multilineage dysplasia without Antecede	AML-Not otherwise specified	AML with multilineage dysplasia following MDS	AML-Not otherwise specified	AML-Not otherwise specified
FAB	M1	N/A	N/A	M5	M4	M4
Somatic mutations		CEBPA bi-allelic	NRAS Q61K		DNMT3A R882H	NPM1c, DNMT3A R882H