Figure 2.
The structure of a CO-scavenging agent, hemoCD1, a 1:1 supramolecular inclusion complex of an ironporphyrin (FeTPPS) and a per-O-methylated cyclodextrin dimer (Py3CD). HemoCD1 is used for selective removal of endogenous CO in mice via the ligand exchange reaction of O2 with CO. The binding affinity for CO (P1/2CO = 0.000015 Torr) is much higher than that for O2 (P1/2O2 = 10 Torr)34. The components of Fig. 2 were drawn using ChemBioDraw.