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. 2018 Aug 10;8:11988. doi: 10.1038/s41598-018-30418-5

Figure 1.

Figure 1

Crystal structure of mADK ternary complex highlighting the catalytic pocket, bound ADP (BS1) and ADO (BS2) and functionally relevant ions. The structure is represented in surface, highlighting the lid domain in dark orange and the large domain in light orange colors. ADP and ADO are represented in yellow sticks with carbon, oxygen, nitrogen and phosphorus atoms colored as yellow, red, blue and orange, respectively. Arg148 (orange stick), Asp316 catalytic residue (pink stick), the anion hole motif DTNGAG (cyan region), ADO in the BS2, ADP in the BS1, two magnesium ions (green spheres), one chloride ion (palecyan sphere) and one potassium ion (purple sphere).