Table 1.
CON | HF | HF-IT | One-Way ANOVA | |
---|---|---|---|---|
Systolic function | ||||
HR, beats/min | 113 ± 5 | 103 ± 8 | 106 ± 5 | NS |
LVESV, ml | 39 ± 7 | 36 ± 6 | 32 ± 3 | NS |
LVESP, mmHg | 78 ± 4 | 109 ± 6* | 106 ± 6* | P < 0.05 |
LV EF, % | 64 ± 3 | 66 ± 3 | 65 ± 4 | NS |
LV SV, ml | 66 ± 6 | 67 ± 4 | 74 ± 5 | NS |
ESPVR, mmHg/ml | 6 ± 1 | 14 ± 3 | 11 ± 2 | NS |
PRSW, mmHg | 65 ± 6 | 106 ± 15* | 103 ± 7* | P < 0.05 |
Diastolic function | ||||
LVEDV, ml | 105 ± 11 | 103 ± 9 | 103 ± 7 | NS |
LVEDP, mmHg | 7 ± 1 | 9 ± 2 | 8 ± 1 | NS |
EDPVR, mmHg/ml | 0.005 ± 0.001 | 0.012 ± 0.002* | 0.016 ± 0.003* | P < 0.05 |
Values are means ± SE; n = 5, 6, and 6 for CON, HF, and HF-IT, respectively. CON, nonsham sedentary control; HF, aortic-banded heart failure sedentary; HF-IT, aortic-banded heart failure interval exercise trained; HR, heart rate; LVESV, left ventricular (LV) end-systolic volume; LVESP, LV end-systolic pressure; EF, ejection fraction; SV, stroke volume; ESPVR, end-systolic pressure-volume relationship; PRSW, preload recruitable stroke work; LVEDV, LV end-diastolic volume; LVEDP, LV end-diastolic pressure; EDPVR, end-diastolic pressure-volume relationship; NS, not significant.
Post hoc, P < 0.05 vs. CON.