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. 2018 Jul 26;175(17):3594–3609. doi: 10.1111/bph.14428

Figure 6.

Figure 6

miR‐351‐5p aggravates apoptosis by inhibiting Sirt6. (A) The expression of the proteins, Bax, cytochrome c (Cytc), apoptotic peptidase activating factor 1 (Apaf‐1), cleaved‐caspase 3 and cleaved‐caspase 9 in IEC‐6 cells. (B) Levels of the proteins Bax, Cytc, Apaf‐1, cleaved‐caspase 3 and cleaved‐caspase 9 in mice. (C) The levels of the proteins Bax, Cytc, Apaf‐1, cleaved‐caspase 3 and cleaved‐caspase 9 in rats. Data are presented as mean ± SD (n = 5).* P < 0.05, significantly different from control group. # P < 0.05, significantly different from 60 min reoxygenation or 90 min reperfusion group.