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. 2018 Jul 26;175(17):3594–3609. doi: 10.1111/bph.14428

Figure 7.

Figure 7

Effects of over‐expression or blockade of miR‐351‐5p on H/R injury in IEC‐6 cells. (A) Cell viabilities of IEC‐6 cells with or without transfection of miR‐351‐5p mimic and inhibitor in each group (n = 5). (B) Levels of miR‐351‐5p in IEC‐6 cells with or without transfection of miR‐351‐5p mimic and inhibitor in each group (n = 5). (C) The mRNA levels of IL‐1β, TNF‐α and ICAM‐1 in IEC‐6 cells after mimic or inhibitor of miR‐351‐5p (n = 5). (D–E) The levels of ROS and cell apoptosis in IEC‐6 cells after mimic or inhibitor of miR‐351‐5p (n = 5). (F–G) Levels of the proteins associated with miR‐351‐5p/MAPK13 and miR‐351‐5p/Sirt6 signal pathways after over‐expression or blockade of miR‐351‐5p in vitro (n = 5). All the data are expressed as the mean ± SD. * P < 0.05, significantly different as indicated.