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. 2018 Aug 8;11:4661–4671. doi: 10.2147/OTT.S164149

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© 2018 Zheng et al. This work is published and licensed by Dove Medical Press Limited

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Low EYA2 protein predicted a poor prognosis in patients with CRC.

Notes: (A) Associations between EYA2 expression and DFS in the patient subgroups with different stage tumors. (B) Associations between EYA2 expression and OS in the patient subgroups with diffrent stage tumors. Patients with stages I–III, stage I, stage II, or stage III tumor were dichotomized into the subgroups with high- or low-EYA2 protein expression according to EYA2 IHC score (cutoff value =145). Kaplan–Meier survival curves reveal DFS and DSS in patients with each TNM stage CRC. P-values are from Kaplan–Meier analysis with log-rank test.

Abbreviations: CRC, colorectal cancer; DFS, disease-free survival; DSS, disease-specific survival; EYA2, eyes absent homologue 2; IHC, immunohistochemistry; TNM, tumor-node-metastasis.