Table 2.
Primary information for PPARG rs1801282 C>G, rs3856806 C>T, PPARGC1A rs2970847 C>T, and PPARGC1B rs7732671 G>C, rs17572019 G>A polymorphisms
| Genotyped SNPs | PPARG rs1801282 C>G | PPARG rs3856806 C>T | PPARGC1A rs2970847 C>T | PPARGC1B rs7732671 G>C | PPARGC1B rs17572019 G>A |
|---|---|---|---|---|---|
| Chromosome | 3 | 3 | 4 | 5 | 5 |
| Function | Missense | Coding-synonymous | Coding-synonymous | Missense | Missense |
| “Chr Pos” (NCBI build 37) | 12393125 | 12475557 | 23815924 | 149212243 | 149212471 |
| MAF for Chinese in database | 0.07 | 0.25 | 0.28 | 0.09 | 0.07 |
| MAF in our controls (n=923) | 0.05 | 0.22 | 0.22 | 0.06 | 0.06 |
| P-value for HWE test in our controls | 0.883 | 0.009 | 0.498 | 0.241 | 0.543 |
| Genotyping method | SNP scan | SNP scan | SNP scan | SNP scan | SNP scan |
| Percentage genotyping value | 99.27% | 99.27% | 99.27% | 99.27% | 99.27% |
Abbreviations: MAF, minor-allele frequency; HWE, Hardy–Weinberg equilibrium; SNP, single-nucleotide polymorphism.