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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Exp Neurol. 2018 Mar 5;304:58–66. doi: 10.1016/j.expneurol.2018.02.016

Fig. 1.

Fig. 1.

CNP deficiency (Nppclbab/lbab) increases the vulnerability of the neonatal brain to HI insult. (A) CNP gene mutated or wildtype (Nppc+/+) mouse pups at postnatal day 7 (P7) were subjected to HI treatment (20 min of hypoxia, 8% O2), and brain infarct size was detected 48 h after HI. n = 8 pups/group. B) Rotarod test for locomotor function evaluation performed one month after HI. Data are expressed as mean ± SEM. n = 9–10 pups/group, *, p < 0.05 vs. Nppc+/+. ns, no significant difference. Two-tailed Student’s t-test.