Table 3. Performance in the active avoidance test for 3 parameters: Total shocked time, time to accept, and total time on correct side.

Animals that failed out of the test (continuously shocked for 6 consecutive trials) were removed from analysis. These are reported along with those animals which successfully learned over the course of the trials, and are reported as percentages. The intercept and slope for the assay, and the differences between vehicle control (0.1% DMSO) and SM10 treated animals are reported.

Time Shocked
Treatment	Failed Out	Learned	Intercept, Slope	Diff, p-value
Vehicle Control	0%	42.5%	1.47, −0,041	-
0.1% SM10	2.80%	40%	2.03, −0.032	0.21, 0.06
Decision Time
Treatment	Failed Out	Learned	Intercept, Slope	Diff, p-value
Vehicle Control	0%	35%	4.945, −0.067	-
0.1% SM10	2.80%	22.9%	5.119, −0.013	0.44, 0.005*
Time on Correct Side
Treatment	Failed Out	Learned	Intercept, Slope	Diff, p-value
Vehicle Control	0%	47.5%	18.164, 0.102	-
0.1% SM10	2.80%	29.2%	17.611, 0.063	0.55, 0.001*

^*p<0.05 repeated measures ANOVA and Tukey’s post hoc test.