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. Author manuscript; available in PMC: 2018 Aug 12.
Published in final edited form as: Sci Transl Med. 2016 Sep 28;8(358):358ra125. doi: 10.1126/scitranslmed.aag1048

Fig. 5. HIV-specific CD8+ T-cell responses in pediatric infection in relation to viral load and absolute CD4 count.

Fig. 5.

a–c. Breadth of IFN-γ elispot responses correlate with viral load in a protein-specific fashion. a–b. Total breadth and Gag-specific breadth of IFN-γ elispot response (n=90). c. Env-specific breadth of IFN-γ elispot response (n=90). d–e. Total breadth and Pol-specific breadth of IFN-γ elispot response in ART-naïve pediatric subjects is inversely correlated with absolute CD4 count (n=90). f. Total breadth of IFN-γ elispot response directly correlates with CD8+ T-cell activation in pediatric infection (n=30). Spearman rank correlation tests.