Table 3.

Gastrointestinal symptoms in hEDS patients compared with controls.

	Control	hEDS	P value (Fisher's exact test)
Number	45	45
M : F	6 : 39	6 : 39
Symptoms
Abdominal pain	12	31	<0.0001∗∗∗
Diarrhoea	4	21	<0.0001∗∗∗
Constipation	7	33	<0.0001∗∗∗
Medicines
Antisecretory/antacids	8	37	<0.0001∗∗∗
Laxatives	7	34	<0.0001∗∗∗
Oesophageal disorders
Functional chest pain	1	4	0.3607
Functional heartburn	6	21	0.0011∗∗
Globus	1	2	1
Functional dysphagia	2	9	0.01∗
Gastroduodenal disorders
Functional dyspepsia	4	17	0.0291∗
Belching disorders	2	7	0.2663
Nausea and vomiting disorders	1	3	0.6164
Rumination syndrome	1	2	0.6164
Bowel disorders
Irritable bowel syndrome	3	15	0.0014∗∗
Functional constipation	6	23	0.0002∗∗
Functional diarrhoea	3	12	0.0014∗∗
Functional abdominal bloating/distension	3	14	0.0059∗∗
Unspecified functional bowel disorder	12	27	<0.0001∗∗∗
Centrally mediated abdominal pain syndrome	2	7	0.2663
Functional biliary pain	1	1	1
Anorectal disorders
Faecal incontinence	1	1	1
Functional anorectal pain	1	2	0.6164

^∗ P < 0.05; ^∗∗P < 0.01; ^∗∗∗P < 0.001.