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Schematic representation of bidirectional interaction between rat bone marrow-derived mesenchymal stem cells (rBM-MSCs) and activated microglia. Activated microglia increased migration of rBM-MSCs in rBM-MSCs cocultured with LPS-stimulated microglia in an in vitro coculture system. rBM-MSCs decreased the inflammatory response of activated microglia in a reverse coculture system.
