Table 7.
The effects of Tuber melanosporum powder on oxidative stress-related factors in the serum and kidney of mice.
| db/+ | db/db | 0.1 g/kg Met | 0.2 g/kg TM | 0.4 g/kg TM | ||
|---|---|---|---|---|---|---|
| Serum | SOD (U/mL) | 240.3 ± 5.0 | 193.6 ± 2.5### | 245.7 ± 3.9∗∗∗ | 206.1 ± 3.9∗ | 218.6 ± 5.5∗∗∗ |
| GSH-Px (U/mL) | 304.4 ± 9.5 | 230.8 ± 3.7### | 227.2 ± 6.0 | 248.8 ± 11.6 | 236.5 ± 5.3 | |
| CAT (U/mL) | 54.6 ± 1.3 | 41.2 ± 0.9### | 45.2 ± 1. 5∗ | 48.3 ± 1.9∗∗ | 48.4 ± 1.1∗∗∗ | |
|
| ||||||
| Kidney | ROS (U/mg) | 46.1 ± 1.7 | 62.6 ± 4.1# | 42.1 ± 2.1∗∗∗ | 51.1 ± 0.5 | 43.3 ± 3.2∗ |
| SOD (U/mg) | 34.9 ± 2.8 | 23.3 ± 1.3## | 29.4 ± 2.6∗ | 37.0 ± 5.0∗ | 34.1 ± 4.8∗ | |
| GSH-Px (mg/mL) | 75.7 ± 3.9 | 42.3 ± 1.3### | 50.8 ± 3.0∗ | 71.6 ± 6.9∗∗ | 67.7 ± 6.4∗∗ | |
| CAT (U/mg) | 8.7 ± 0.5 | 7.0 ± 0.3# | 8.8 ± 0.5∗ | 8.9 ± 0.4∗∗ | 9.0 ± 0.3∗∗ | |
The data were analyzed using a one-way ANOVA and they are expressed as means ± SEMs (n = 10). #p < 0.05, ##p < 0.01, and ###p < 0.001 versus db/+ mice; ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001 versus nontreated db/db mice. TM: T. melanosporum.