Table 2.
Rates of sex chromosome loss and gain measured by XY FISH
| Sample | Normal X and Y, % | Lost Y, % | Lost X, % | Total lost, % | Gained Y, % | Gained X, % | Total gained, % |
|---|---|---|---|---|---|---|---|
| Adult lymphocyte metaphases | 99.04 | 0.96 | 0.00 | 0.96 | — | — | — |
| Adult lymphocyte interphases | 98.81 | 0.59 | 0.59 | 1.19 | — | — | — |
| Embryonic cortex | 93.26 | 4.50 | 1.40 | 5.90 | 0.17 | 0.67 | 0.84 |
| Adult cortex | 98.84 | 0.64 | 0.37 | 1.01 | 0.10 | 0.05 | 0.15 |
| Adult cortex ≥10 μm | 98.85 | 0.29 | 0.14 | 0.43 | 0.43 | 0.29 | 0.72 |
Cells were isolated from adult lymphocytes and E13–E14 and adult cerebral cortices. ≥10 μm, isolated adult cortical nuclei with diameters greater than or equal to 10 μm.